Atlanta has been more committed to running the ball, but the Saints have held opponents to fewer than 100 rushing yards six times this year. Falcons quarterback Marcus Mariota hasn't thrown for 200 yards in a game since Week 8 and has only done so three times total this season. The model's Week 15 NFL knockout pool picks say to avoid the Falcons (5-8), even though they are a game ahead of the Saints (4-9) in the NFC South. SportsLine's model has New York covering the spread almost 60% of the time in this matchup. They have covered the spread in seven of their last 10 games, making them one of the most undervalued teams in the league this season. New York is facing a weak Detroit defense, which will allow the Jets to get back on track offensively. The Lions have gone 2-12-1 in their last 15 road games and quarterback Jared Goff will face the fourth-best pass defense in the NFL. 20, making this a difficult scheduling spot. Detroit has not played a road game since Nov. The Jets have won three of their last four home games, beating Miami, Buffalo and Chicago, so they will be confident coming into this matchup. New York has lost three of its last four games, but all three of those losses came on the road. One of the model's strongest Week 15 NFL picks is that the Jets (-1) cover the spread at home against the Lions. Now, it has turned its attention to the latest Week 15 NFL odds and locked in NFL picks for every NFL matchup. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. The model is also a sizzling 21-5 on straight-up NFL picks over the past two weeks.

The model enters Week 15 of the 2022 NFL season on an incredible 157-113 run on top-rated NFL picks that dates back to the 2017 season. The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception.

All of the Week 15 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best Week 15 NFL picks now. Other large Week 15 NFL betting lines include Eagles (-9) against the Bears and Packers (-7) against the Rams. The Kansas City Chiefs are the week's biggest favorites at -14.5 against the one-win Houston Texans in the NFL spreads. The latest Week 15 NFL odds from Caesars Sportsbook show the widening gap between the top contenders and the rest of the league. As the Week 15 NFL schedule continues on Sunday, several teams are separating themselves as 2023 Super Bowl contenders.

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